Synovial Chondrosarcoma Arising in Synovial Chondromatosis

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Synovial Chondrosarcoma Arising in Synovial Chondromatosis

Primary synovial chondromatosis (SC) is a rare proliferative disorder that causes pain, swelling, and restriction of movement to the joints it affects. The disease frequently runs a protracted course, often requiring multiple surgical procedures to obtain some control. Few reports exist detailing the natural history of SC, although malignant transformation to synovial chondrosarcoma (CHS) is re...

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Chondrosarcoma Developing in Synovial Chondromatosis

Synovial chondromatosis is a rare condition in which osteocartilaginous nodules are formed by synovial metaplasia and become intra-articular loose bodies. It is usually monarticular, most commonly affecting the knee and is regarded as invariably benign. There are reports ofmalignant change, but only the two case studies of Mullins, Berard and Eisenberg (1965) and of Dunn et at. (1974) fully doc...

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Synovial Chondromatosis and Chondrosarcoma: A Diagnostic Dilemma

PURPOSE The progression of synovial chondromatosis to chondrosarcoma is very rare. Distinction between these two entities may be difficult on histology alone, and should be based on clinical, radiographic and microscopic evidence. Immunohistochemical markers that would facilitate differentiation between synovial chondromatosis and chondrosarcoma are currently being investigated. PATIENTS We d...

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Cytogenetic analysis of a low-grade secondary peripheral chondrosarcoma arising in synovial chondromatosis.

Secondary chondrosarcoma is a malignant chondroid tumor arising in a benign precursor. Synovial chondromatosis is a benign chondroid lesion that rarely transforms to chondrosarcoma. We present the case of a 54-year-old male with the diagnosis of low-grade secondary peripheral chondrosarcoma developed in the context of synovial chondromatosis. Cytogenetics revealed a novel aberration t(1;14)(q23...

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Synovial Chondromatosis

A 34-year-old male patient presented severe pain in his left knee in association with functional incapacitation, with no apparent triggering factor. He sought medical attention in December 2006, at which time he was prescribed NSAIDs. After a year, he reported increased swelling and pain at the site. He was referred to a knee specialist with a suspected meniscal injury. Upon examination, severe...

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ژورنال

عنوان ژورنال: Sarcoma

سال: 2014

ISSN: 1357-714X,1369-1643

DOI: 10.1155/2014/647939